USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: LYPA2_HUMAN USC-OGP 2-DE database:  LYPA2_HUMAN LYPA2_HUMAN General information about the entry View entry in simple text format Entry name LYPA2_HUMAN Primary accession number O95372 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Acyl-protein thioesterase 2; Short=APT-2; EC=3.1.2.-; AltName: Full=Lysophospholipase II; Short=LPL-II; Short=LysoPLA II;. Gene name Name=LYPLA2 Synonyms=APT2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_6-11 {PLATELET 6-11} Homo sapiens (Human)   map experimental info   PLATELET_6-11 MAP LOCATIONS: SPOT OGP-1021: pI=6.77; Mw=24310 Cross-references UniProtKB/Swiss-Prot O95372; LYPA2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LYPA2_HUMAN Primary accession number O95372 Secondary accession number(s) Q7Z4Z2 Sequence was last modified on  May 1, 1999 (version 1) Annotations were last modified on  March 15, 2017 (version 137) Name and origin of the protein Description RecName: Full=Acyl-protein thioesterase 2; Short=APT-2; EC=3.1.2.-; AltName: Full=Lysophospholipase II; Short=LPL-II; Short=LysoPLA II; Gene name Name=LYPLA2 Synonyms=APT2 Encoded on Name=LYPLA2; Synonyms=APT2 Keywords 3D-structure; Complete proteome; Cytoplasm; Fatty acid metabolism; Hydrolase; Lipid metabolism; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF098668; AAC72844.1; -; mRNA EMBL AF090423; AAP97210.1; ALT_FRAME; mRNA EMBL AL031295; CAB40158.1; -; Genomic_DNA EMBL BC017034; AAH17034.1; -; mRNA EMBL BC017193; AAH17193.1; -; mRNA CCDS CCDS241.1; -; . RefSeq NP_009191.1; NM_007260.2; . UniGene Hs.533479; -; . PDB 5SYN; X-ray; 1.64 A; A/B/C/D=1-231 PDBsum 5SYN; -; . ProteinModelPortal O95372; -; . SMR O95372; -; . BioGrid 116444; 22; . IntAct O95372; 5; . STRING 9606.ENSP00000363638; -; . BindingDB O95372; -; . ChEMBL CHEMBL1932891; -; . SwissLipids SLP:000001479; -; . ESTHER human-LYPLA2; LYsophospholipase_carboxylesterase; . MEROPS S09.025; -; . iPTMnet O95372; -; . PhosphoSitePlus O95372; -; . SwissPalm O95372; -; . BioMuta LYPLA2; -; . OGP O95372; -; . EPD O95372; -; . MaxQB O95372; -; . PaxDb O95372; -; . PeptideAtlas O95372; -; . PRIDE O95372; -; . DNASU 11313; -; . Ensembl ENST00000374514; ENSP00000363638; ENSG00000011009; . GeneID 11313; -; . KEGG hsa:11313; -; . UCSC uc001bht.4; human; . CTD 11313; -; . DisGeNET 11313; -; . GeneCards LYPLA2; -; . HGNC HGNC:6738; LYPLA2; . HPA HPA063151; -; . neXtProt NX_O95372; -; . OpenTargets ENSG00000011009; -; . PharmGKB PA30500; -; . eggNOG KOG2112; Eukaryota; . eggNOG COG0400; LUCA; . GeneTree ENSGT00390000009648; -; . HOGENOM HOG000260139; -; . HOVERGEN HBG052378; -; . InParanoid O95372; -; . KO K06130; -; . OMA WLPLHRN; -; . OrthoDB EOG091G080L; -; . PhylomeDB O95372; -; . TreeFam TF314619; -; . Reactome R-HSA-373760; L1CAM interactions; . GenomeRNAi 11313; -; . PRO PR:O95372; -; . Proteomes UP000005640; Chromosome 1; . Bgee ENSG00000011009; -; . CleanEx HS_LYPLA2; -; . ExpressionAtlas O95372; baseline and differential; . Genevisible O95372; HS; . GO GO:0005737; C:cytoplasm; IDA:BHF-UCL; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0045296; F:cadherin binding; IDA:BHF-UCL; . GO GO:0052689; F:carboxylic ester hydrolase activity; IBA:GO_Central; . GO GO:0008474; F:palmitoyl-(protein) hydrolase activity; IBA:GO_Central; . GO GO:0007411; P:axon guidance; TAS:Reactome; . GO GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW; . GO GO:0002084; P:protein depalmitoylation; IBA:GO_Central; . Gene3D 3.40.50.1820; -; 1; . InterPro IPR029058; AB_hydrolase; . InterPro IPR003140; PLipase/COase/thioEstase; . Pfam PF02230; Abhydrolase_2; 1; . SUPFAM SSF53474; SSF53474; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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